A multi-car pileup, involving more than 100 vehicles, along Interstate-35W in Fort Worth has shutdown the highway and left several people trapped in their cars.

Fort Worth police spokesperson, Officer Daniel Segura has confirmed at least 5 people, who have not been identified, were killed in the crash.

The pileup happened around 6:30 a.m. after freezing rain and sleet fell overnight and into the morning, leaving roadways across North Texas wet and slick.

All lanes of the interstate — starting near the 28th Street bridge, not far from downtown — are closed because of the accident that police say was due to weather.

Pictures and video from CBS 11 News crews at the scene show dozens of vehicles and dozens of 18-wheelers — some hauling cars and trucks — smashed, toppled over, and stacked on top of each other.

Officials say I-35W is backed up in both directions from Interstate-30 to well past Loop 820. First responders are calling the crash a ‘mass casualty incident’. Multiple ambulances were dispatched to the scene, and have transported dozens of patients to nearby hospitals in unknown conditions, but the rescuers did and are having are difficulty reaching some victims because of the literal pileup and the blocked roadway.